Treatment of intestinal helminthiasis: mebendazole only or mebendazole-pyrantel pamoate?

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Mebendazole treatment of dracunculiasis

MULLER,(1979) claimed that no alteration of the adult Dracunculus medinensis or its larvae was seen after benzimidazole treatment. Further trials established that several benzimidazole drugs reduced the inflammation and lessened the duration of disabilities. Mebendazole was used by KALE (1975) in a dose of 400 mg daily for 5 d, and by PAUL et al. (1983) in a daily dose of 1000 mg for 10 d. Both...

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Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar.

OBJECTIVE To evaluate the efficacy of and resistance to mebendazole (500 mg) and levamisole (40 or 80 mg), alone or in combination, for the treatment of Ascaris lumbricoides, Trichuris trichiura and hookworm infections on Pemba Island - an area exposed to periodic school-based mebendazole treatment since 1994. METHODS A randomized, placebo-controlled trial was carried out in 914 children enro...

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Mebendazole treatment of dracunculiasis

MULLER,(1979) claimed that no alteration of the adult Dracunculus medinensis or its larvae was seen after benzimidazole treatment. Further trials established that several benzimidazole drugs reduced the inflammation and lessened the duration of disabilities. Mebendazole was used by KALE (1975) in a dose of 400 mg daily for 5 d, and by PAUL et al. (1983) in a daily dose of 1000 mg for 10 d. Both...

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Residue study of mebendazole and its metabolites hydroxy-mebendazole and amino-mebendazole in eel (Anguilla anguilla) after bath treatment.

Mebendazole (MBZ) is extensively used in eel culture for treatment of Pseudodactylogyrus spp. infections. This use may lead to residues of MBZ in eel tissues. Consequently, the residue profile of MBZ in eel after treatment with the drug is of special concern. Therefore, a residue study was performed in European eels (Anguilla anguilla), bath-treated with MBZ at a dose of 1 mg/liter for 24 hr an...

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Flubendazole versus mebendazole in intestinal helminthic infections.

In a double-blind study the vermicidal effect of flubendazole, a new benzimidazole derivative, was evaluated and compared to mebendazole. Both drugs were administered in a single dose of 600 mg. While in the treatment of Ascaris and hookworm infestations flubendazole and mebendazole showed a similar efficacy, mebendazole seemed to be slightly superior in the treatment of trichuriasis. Both drug...

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ژورنال

عنوان ژورنال: Paediatrica Indonesiana

سال: 2007

ISSN: 2338-476X,0030-9311

DOI: 10.14238/pi47.5.2007.216-20